Oral Cobalamin Supplementation in Dogs with Chronic Enteropathy
- Linda Toresson, DVM
- Helsinki University
- Cobalamin (vitamin B12) deficiency may occur secondary to chronic enteropathy and exocrine pancreatic insufficiency in dogs.
- In dogs with chronic enteropathies, injectable cobalamin was more effective at increasing serum cobalamin in the first 28 days, but oral cobalamin had significantly greater effects by the end of the study (90 days).
- Based on biomarker concentrations, there were no significant differences between oral and injectable cobalamin formulations in normalizing intracellular cobalamin status.
- Oral cobalamin supplementation is as effective as injectable cobalamin at correcting low cobalamin concentrations in dogs, but more research is required to investigate these effects in cats.