PURINA INSTITUTE MICROBIOME FORUM ROUND TABLE: MICROBIOME-CENTRIC MANAGEMENT OF ACUTE AND CHRONIC DIARRHEA IN DOGS AND CATS
Speakers: Jan Suchodolski, MedVet, DrVetMed, PhD, AGAF, DACVM;
Valerie Parker, DVM, DACVIM, DACVN;
Linda Toresson, DVM, PhD;
Joerg Steiner med.vet., Dr.med.vet., PhD, DACVIM-SAIM, DECVIM-CA, AGAF;
Stefan Unterer, riv.-Doz., Dr. med. vet., Dr. habil., DipECVIM-CA;
This video is in English
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Our understanding of the gut microbiome is rapidly evolving, but is our case management of diarrhea evolving with it? In this roundtable discussion with Q&A, leading experts discuss key aspects of managing acute and chronic diarrhea in dogs and cats, with a focus on providing practical and evidence-based advice for veterinarians. Specific topics include methods for evaluating the presence of dysbiosis, conducting elimination diet trials, benefits of fiber and other dietary interventions, identifying when fecal microbiota transfer (FMT) is appropriate, and how to perform FMT when indicated.
The Purina Institute Microbiome Forum Round Table was held on March 31, 2022.
Right lateral thoracic radiograph of a small dog in ACVIM Stage C, heart failure.
Improved preservation of body weight
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When Fel d 1 was first discovered, the proposed name was “cat allergen 1.” The name Fel d 1 comes from Felis domesticus1,2, which was the commonly used species name of the domestic cat at the time the allergen was officially named. Although the domestic cat’s official species name is now Felis catus, the Fel d name has not been changed. The Fel d allergens were numbered in order of their discovery; Fel d 1 was the first.
- Consult the feeding guidelines on the pet food package.
Use a standard 8-oz. or 250-ml measuring cup OR the most accurate method is to weigh the food using a kitchen scale 1,2.
Testing table Test 1 Test2 DHA Felis domesticus
When Fel d 1 was first discovered, the proposed name was “cat allergen 1.” The name Fel d 1 comes from Felis domesticus, which was the commonly used species name of the domestic cat at the time the allergen was officially named. Although the domestic cat’s official species name is now Felis catus, the Fel d name has not been changed. The Fel d allergens were numbered in order of their discovery; Fel d 1 was the first.
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Test-How did Fel d 1 get its name?
When Fel d 1 was first discovered, the proposed name was “cat allergen 1.” The name Fel d 1 comes from Felis domesticus1,2, which was the commonly used species name of the domestic cat at the time the allergen was officially named. Although the domestic cat’s official species name is now Felis catus, the Fel d name has not been changed. The Fel d allergens were numbered in order of their discovery; Fel d 1 was the first.
- Consult the feeding guidelines on the pet food package.
Use a standard 8-oz. or 250-ml measuring cup OR the most accurate method is to weigh the food using a kitchen scale 1,2.
Testing table Test 1 Test2 DHA Felis domesticus
How did Fel d 1 get its name?
When Fel d 1 was first discovered, the proposed name was “cat allergen 1.” The name Fel d 1 comes from Felis domesticus, which was the commonly used species name of the domestic cat at the time the allergen was officially named. Although the domestic cat’s official species name is now Felis catus, the Fel d name has not been changed. The Fel d allergens were numbered in order of their discovery; Fel d 1 was the first.
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Shifts in gut bacteria when overweight cats were fed an HPLC diet:
| Bacteria | Decreased | Increased |
|---|---|---|
| Phylum | Fusobacteria increased by > 8 times | |
| Family | Veillonellaceae, Bifidobacteriaceae, Porphyromonadaceae, and Rikenellaceae | Fusobacteriaceae, Clostridiaceae, Lachnospiraceae, Ruminococcaceae, Mogibacteriaceae, and Peptococcaceae |
| Genera | Megasphaera, Veillonella, and Bifidobacterium | Faecalibacterium and Fusobacterium |
| Species | E. cylindroides, L. ruminis, and B. plebeius | F. prausnitzii, R. gnavus, C. hiranonis, and E. dolichum |
- Age-related physical, metabolic and functional changes in the brains of middle-aged pets may set the stage for cognitive impairment or dysfunction as seniors, and the severity and progression of these changes determines the pet’s brain health later in life1,4;
- The aging brain has a less efficient energy metabolism due to changes in glucose utilization and impaired mitochondrial function;
- Owners of older pets may not consider their pets as ‘senior’ until they notice behavioral changes caused by age-related brain changes;
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Additional Resources
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Oriach, C. S., Robertson, R. C., Stanton, C., Cryan, J. F., & Dinan, T. G. (2016). Food for thought: The role of nutrition in the microbiota-gut-brain axis. Clinical Nutrition Experimental, 6, 25–38.
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Kynetec. (2018). Global Veterinary Topics: Quantitative Results.
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Oriach, C. S., Robertson, R. C., Stanton, C., Cryan, J. F., & Dinan, T. G. (2016). Food for thought: The role of nutrition in the microbiota-gut-brain axis. Clinical Nutrition Experimental, 6, 25–38.
-
Kynetec. (2018). Global Veterinary Topics: Quantitative Results.
-
Oriach, C. S., Robertson, R. C., Stanton, C., Cryan, J. F., & Dinan, T. G. (2016). Food for thought: The role of nutrition in the microbiota-gut-brain axis. Clinical Nutrition Experimental, 6, 25–38.
-
Kynetec. (2018). Global Veterinary Topics: Quantitative Results.