Get an overview of scientific content presented during the 2024 event, with suggestions for applying microbiome science to clinical practice. 

The Microbiome Forum Round Table 2025 brings together a panel of gastroenterologists and nutritionists to discuss the ongoing evolution of GI case management, including the foundational role of nutrition and addressing dysbiosis.

The speakers who presented lectures during Day 2 of the Purina Institute Microbiome Forum 2024 join Dr. Jan Suchodolski to answer questions submitted by audience members. 

Shifts in gut microbiota taxa and/or diversity can result in functional changes in the microbiome. Learn why early recognition of microbiome shifts may improve management of patients with GI conditions. 

Learn how tryptophan that is not used for protein synthesis can be metabolized into protective and/or toxic compounds. Therapeutic interventions that target tryptophan metabolism are promising, but more research is needed. 

Antibiotics are known to negatively affect feline stool quality and gut microbiota. Could a therapeutic diet formulated with increased prebiotic fiber help the microbiome recover after antibiotic administration? 

Many drugs affect the gut microbiome, but how does the gut microbiome influence orally administered medications? Learn about the emerging field of pharmacomicrobiomics. 

Learn how microbiome-centric strategies, such as diet, FMT, prebiotics, and probiotics, can be used to improve management of dogs with chronic GI conditions through a guided review of four relevant clinical cases. 

Dietary trial success is determined by proper diet selection, owner and pet compliance with recommendations, and response assessment, as are client education and a relationship-centered approach to communication. 

What effects do apparent digestibility coefficients of extruded diets have on fecal dysbiosis index, bacterial taxa, and fermentation metabolites in healthy adult dogs? Findings from a recent study offer insights. 

Escherichia coli can be a symbiont, opportunistic pathogen, or pathogen. Learn why Dr. Kenneth Simpson says the presence or absence of E. coli on fecal culture is not helpful in diagnosis of E. coli-associated dysbiosis. 

Clinical cases are used to illustrate multilevel dysfunction, microbiome shifts, diagnostics and clinical staging of chronic gastrointestinal conditions in dogs. The need for multimodal management is also addressed.