Progression of chronic kidney disease in cats is multifactorial, poorly understood, and highly variable. Learn more about the eight factors that have been implicated in renal inflammation, fibrosis, and disease progression.

Explore the interplay between diet and the gut-associated immune system. From providing essential nutrients to modulating immune function, dietary interventions offer opportunities to optimize immune health and reduce immune-related disorders.

Arginine deficiency leads to severe metabolic abnormalities and immune dysfunction in human, feline, and canine patients. Learn about arginine deficiency syndrome, its consequences, and arginine replacement therapy in human medicine.

The gastrointestinal tract does more than digest food and absorb nutrients. It is the body’s largest immune organ and harbors an extensive microbial ecosystem. Here is a brief refresher on the intestinal immune system.

Normal immune and inflammatory responses are influenced by many factors, including aging and nutrition. Learn how specific nutrients can modify inflammatory and cell-mediated immune responses.

An expert panel discusses how new research and evidence-based guidelines are changing approaches to management of diarrhea in dogs and cats.

Get expert insights into incorporating nutrition into palliative and hospice care to preserve the quality of life for pets with chronic and life-limiting health conditions. 

The speakers appearing during Day 2 of the Purina Institute Microbiome Forum 2023 join Dr. Jan Suchodolski to answer questions submitted by audience members. Dr. Natalia Wagemans delivers closing remarks. 

Learn how dysbiosis is defined, how to evaluate intestinal dysbiosis using the dysbiosis index, and how to interpret the results obtained during acute and chronic conditions. 

What is the evidence for antibiotic-responsive enteropathy and does it exist in dogs and cats? Dr. Julien Dandrieux addresses those questions. 

Research shows antibiotic administration during early life is associated with delayed microbiome maturation of kittens and development of chronic diarrhea in adult cats. 

What histopathological changes are occurring in the small intestine of dogs with chronic inflammatory enteropathies? A recent study evaluating samples from three institutions offers important insights.